Repeatability, reproducibility, and observer variability of body composition assessment with single-slice lumbar MRI
Nowak, M., et al. (2025)
Discover imaging
Read Summary ▾
Single-slice MRI at the L3 vertebral level provides accurate and reproducible area measurements of fat and muscle across diverse body types, multiple MRI scanner field strengths, and manufacturers. The measurements are consistent between trained analysts and experienced radiologists.
Automated volumetric MRI quantification of body fat and skeletal muscle in the UK Biobank: technical validation against expert manual segmentations and comparison with single-slice techniques
Nowak, M., et al. (2025)
Abdominal Radiology
Read Summary ▾
Automated volumetric MRI delivers gold-standard fat and muscle quantification at scale, validated against expert manual segmentations. Lumbar single-slice measurements are strongly correlated with volumes, enabling fast routine assessments. Interchangeable, vendor-neutral methods standardize body composition endpoints for clinics and trials—enabling confident monitoring and scalable, trial-ready biomarkers.
Repeatability, Reproducibility, and Observer Variability of Cortical T1 Mapping for Renal Tissue Characterization
Nowak, M., et al. (2024)
Journal of Magnetic Resonance Imaging
Read Summary ▾
Kidney cortical T1 mapping is a highly repeatable and reproducible method across MRI manufacturers, field strengths, and operator conditions. The standardized methodological consistency paves the way for its adoption in multi-centre clinical trials.
Greater ectopic fat deposition, liver fibroinflammation and lower skeletal muscle mass in people with type 2 diabetes
Waddell, T., et al. (2022)
Obesity
Read Summary ▾
UK Biobank analysis shows that people with type 2 diabetes have higher liver fat (PDFF) and fibro-inflammation (cT1) and lower skeletal muscle index than non-diabetic controls. In addition, LiverMultiScan detected greater liver damage in participants with T2D despite normal liver biochemistry (AST/ALT).
Weight loss-related changes in MRI-derived measures of body composition and liver health: a large-scale analysis from UK Biobank
Nowak et al. (2025)
MASH-TAG
Robust assessment of abdominal obesity using a single-slice L3 MRI method
Nowak et al. (2024)
ObesityWeek
Fast and robust assessment of abdominal obesity in individuals with a range of cardiometabolic and liver tissue characteristics – a retrospective analysis of UK Biobank data
Nowak et al. (2024)
American Diabetes Association (ADA)
Population-scale MRI body composition assessment: robust associations between single-slice and volumetric muscle and adipose tissue in the UK Biobank
Nowak et al. (2025)
Society for Abdominal Radiology (SAR)